A drug inhibitor of cyclic GMP phosphodiestera. surrounded by rod photoreceptors?

''The rod photoreptors in the eye are extremly sensitive to desk light. How would I expect the addition of a drug that is to say an inhibitor of Cyclic GMP photodiesterase and a drug that is a non-hydrolyzable analog of GTP to affect the light-sensing cleverness of the rod cells?

Hey I be going to reply and then you removed the sound out from biology !?! It was better to post it here.

if you have an inhibitor of cGMP phopshodiesterase afterwards you will have no cGMP hydrolysis and thus the cation specific channel will remain open. Thus it would be impossible to generate a effrontery signal (no hyperpolarization)

If you have a non hydrolyzable analogue of GTP next the cGMP phopshodiesterase will be always moving (Ta-GTP will not be inactivated by hydrolysis to Ta-GDP) but also you can't form any cGMP. So you will endup with the channel always closed and you will enjoy constant membrane hyperpolarizaion and signaling.

Edit: I've corrected the answer although it's better formulated in the "biology" slot.Sorry.

Related Questions and Answers
Can you embezzle Claritin, Iboprofen, and Amoxycillin at alike time?
Pharmacists told me to take Claritin and my perscription for a sinus infection, but my head feels approaching it's about to split open. Can I take Ibuprofen too? Yes.... Make sure not to take the ibuprofen on an empty stomach, but this combination of meds should be okay. yes it's fine to...

Drug examine?
In the past 3 months, your usual straight-A friend has failed a couple of test, broken up with his girlfriend, and was busted on campus with a united. These symptoms best describe: 1.Marijuana abuse 2.Marijuana dependence 3.Disruptive marijuana disorder 4.Aggressive Personality disorder 1, 2, and 3, which leads to 4. wut

  • what is the relation between an antigen and vaccine?
  • ECG interview?
  • what does it penny-pinching, the pharmacist sign (symbol) the one near snake around the stick?